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Longevity Ingredient References

Our formulations are created with carefully sourced, research-backed ingredients.

Efird, J. T., Choi, Y. M., Davies, S. W., Mehra, S., Anderson, E. J., & Katunga, L. A. (2014). Potential for Improved Glycemic Control with Dietary Momordica charantia in Patients with Insulin Resistance and Pre-Diabetes. International Journal of Environmental Research and Public Health, 11(2), 2328–2345.

Froese, D. S., Fowler, B., & Baumgartner, M. R. (2019). Vitamin B12 , folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation. Journal of Inherited Metabolic Disease, 42(4), 673–685.

Gertz, M., Nguyen, G. T. T., Fischer, F., Suenkel, B., Schlicker, C., Fränzel, B., Tomaschewski, J., Aladini, F., Becker, C., Wolters, D., & Steegborn, C. (2012). A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol. PLOS ONE, 7(11), e49761.

Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, M. T., Wang, S., Liu, H., & Yin, Y. (2016). Quercetin, Inflammation and Immunity. Nutrients, 8(3), 167.

Liu, P., Zhao, H., & Luo, Y. (2017). Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic. Aging and Disease, 8(6), 868–886.

Liu, Y., You, Y., Lu, J., Chen, X., & Yang, Z. (2020). Recent Advances in Synthesis, Bioactivity, and Pharmacokinetics of Pterostilbene, an Important Analog of Resveratrol. Molecules, 25(21), 5166.

Morselli, E., Maiuri, M. C., Markaki, M., Megalou, E., Pasparaki, A., Palikaras, K., Criollo, A., Galluzzi, L., Malik, S. A., Vitale, I., Michaud, M., Madeo, F., Tavernarakis, N., & Kroemer, G. (2010). Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death & Disease, 1(1), e10–e10.

Park, D., Jeong, H., Lee, M. N., Koh, A., Kwon, O., Yang, Y. R., Noh, J., Suh, P.-G., Park, H., & Ryu, S. H. (2016). Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition. Scientific Reports, 6(1), 21772.

Quiles, J. L., Ochoa, J. J., Huertas, J. R., & Mataix, J. (2004). Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet. Experimental Gerontology, 39(2), 189–194.

Weiskirchen, S., & Weiskirchen, R. (2016). Resveratrol: How Much Wine Do You Have to Drink to Stay Healthy?123. Advances in Nutrition, 7(4), 706–718.

National Institutes of Health Office of Dietary Supplements. Carnitine fact sheet for health professionals. Updated: March 29, 2021.